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Treatment guide

Spironolactone for PCOS (now called PMOS): acne, facial hair and hair thinning

“Bumabalik yung tagyawat kahit naka-pills.” If acne, chin hair or a widening part line keep going despite the pill, spironolactone is one of the options doctors add. It works on the androgen side of PMOS, formerly PCOS, and it comes with one rule you must not skip: reliable contraception.

Editorially reviewed on October 29, 2026. [TODO: medical reviewer] How we review

Quick answer

Spironolactone is an anti-androgen: it blocks the effects of testosterone on skin and hair follicles. Doctors, usually dermatologists or OB-GYNs, add it for PCOS acne, hirsutism or hair thinning, often on top of a combined pill.

You need effective contraception while taking it, because it can harm a developing baby. Results take about 6 months. A 25 mg tablet costs ₱12 per tablet (Spiros) to ₱19 per tablet (Aldactone). Prescription only.

Key facts

What it is
An anti-androgen (originally a diuretic, or water pill)
Rx or supplement
Prescription only
Typical PH cost per month
About ₱720 to ₱1,140 (cost example at 2 tablets of 25 mg a day; your doctor sets the amount)
Evidence (2023 Guideline)
Limited evidence
Time to see results
About 6 months
Who prescribes
Dermatologist or OB-GYN

How it works

In PCOS, higher androgens drive oily skin, deep jawline breakouts, coarse hair on the chin and body, and thinning at the crown. Spironolactone sits on the androgen receptors in skin and hair follicles so testosterone has less effect there. It does not regulate your cycle, so doctors usually pair it with a combined pill or other treatment for periods.

Hair and skin change slowly. Hair follicles cycle over months, so most doctors review progress at around 6 months. Laser or IPL hair reduction works better alongside hormonal treatment, and maintenance sessions are often needed in PCOS.

Why you need contraception

Do not get pregnant on spironolactone

Because it blocks androgens, spironolactone can affect the development of a baby. Use effective contraception the whole time you take it, and stop and talk to your doctor at once if you think you might be pregnant. If you are trying to conceive, it is not the right medicine for now; see the fertility guide.

This is one reason doctors often combine it with a combined pill, which covers contraception and cycles together. Remember that PCOS itself is not contraception: you ovulate less often, not never. Our sister site birthcontrolphilippines.com compares contraceptive options.

Who it suits

  • Women whose acne or unwanted hair has not improved enough after a fair trial of a combined pill
  • Women who cannot take estrogen, with another reliable contraceptive in place
  • Some women with female pattern hair thinning, sometimes alongside minoxidil (see hairlossphilippines.com)

A user on r/Hairloss wrote that she had “a spiro prescription but I'm scared to start” (thread). That worry is valid. Ask your doctor what to expect, how long to try it, and what happens if you stop. For hair thinning, also ask for ferritin, thyroid and vitamin D checks.

Side effects and fears

Commonly reported effects include needing to pee more, tiredness, breast tenderness, irregular spotting and feeling lightheaded when standing up quickly. Spironolactone can raise potassium, so doctors may check a blood test. [TODO: source: spironolactone product label]

“Bumabalik yung tagyawat kahit naka-pills.”

My acne keeps coming back even on pills.

PCOS acne is androgen-driven. If one option is not working after a fair trial, ask about others: a different pill, topical treatments, a dermatologist, or spironolactone with effective contraception.

“Nakakahiya yung balbas ko.”

I have to shave my chin every day.

Facial hair from high androgens is common and treatable. The combined pill is preferred for hirsutism (Rec 4.4.1). Laser or IPL works better with hormonal treatment, and maintenance sessions are often needed.

“Numinipis ang buhok ko.”

My hair is thinning.

Female pattern hair loss in PCOS is androgen-related. Options include the combined pill, spironolactone with contraception, and minoxidil. Ask for ferritin, thyroid and vitamin D checks too.

“Hindi ba ako mabubuntis kasi may PCOS ako?”

Is PCOS a form of contraception?

No. PCOS means you ovulate less often, not never. If you do not want to get pregnant, you still need contraception.

Spiros vs Aldactone: what it costs

Spiros is the cheaper brand of the same medicine. In the same cost example, Spiros works out to about ₱720 a month and Aldactone to about ₱1,140. Ask your doctor if the cheaper brand is fine for you. See the full cost guide.

Spironolactone prices in the Philippines
SpironolactonePriceWhereSource
Spironolactone 25 mg (Spiros)₱12 per tabletWatsonsWatsons, 2026-10-29
Spironolactone 25 mg (Aldactone)₱19 per tabletWatsonsWatsons, 2026-10-29

Prices checked October 2026. Prices at Philippine drugstores and labs change often; confirm before you go.

When to see a dermatologist

PCOS skin and hair problems often sit between specialties. A dermatologist is a good next step if your acne is cystic or scarring, if unwanted hair is affecting your life and you are considering laser, or if your scalp hair is thinning. Bring your OB-GYN's notes and your pill history. Filipinas describe feeling “sobrang nadodown” with daily new breakouts; that is a real burden, and asking for more help is reasonable.

Safety

Pregnancy

Use effective contraception throughout. Stop and contact your doctor if you might be pregnant.

Kidney problems, potassium and other medicines

Tell your doctor about kidney problems and about any blood pressure medicines or potassium supplements. [TODO: source: spironolactone product label]

Prescription only

Buy only with a prescription from a licensed pharmacy. Online sellers without a prescription check are a red flag (FDA Advisory 2022-0108).

Check any medicine's registration on the FDA Philippines verification portal.

This guide is for information. Talk to a doctor before starting or changing any treatment.

Frequently asked questions

Pwede ba ang spironolactone sa PCOS acne?

Yes, doctors use it as an anti-androgen for PCOS acne, often with a combined pill. It needs a prescription and effective contraception.

Why do I need contraception on spironolactone?

It can harm a developing baby. Use effective contraception the whole time and talk to your doctor at once if you might be pregnant.

How long does spironolactone take to work?

About 6 months for hair and skin. Hair follicles change slowly, so early results are hard to judge.

Spiros or Aldactone?

Both contain spironolactone. Spiros 25 mg costs less per tablet at Watsons. Ask your doctor whether the cheaper brand is fine for you.

Will my acne or hair come back if I stop?

Spironolactone manages symptoms while you take it. Many people see symptoms return after stopping. Plan any change with your doctor.

Is PMOS the same as PCOS?

Yes. PMOS (polyendocrine metabolic ovarian syndrome) is the new name for PCOS, announced in The Lancet on 12 May 2026. It is the same condition with the same diagnosis and the same treatments. Both names will be used until the 2028 International Guideline update.

Sources

  1. Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. Teede HJ et al., Fertility and Sterility (co-publication), 2023.
  2. Summary of the International Evidence-based Guideline for PCOS 2023. Monash University / Monash IVF, 2023.
  3. FDA Advisory No. 2022-0108 on advertising and online selling of prescription drugs. Food and Drug Administration Philippines, 2022.